| 1. Journée | 26.07.2021 | Vorskla Poltava | - | SK Dnipro-1 | 2:2 |  |
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| 4. Journée | 14.08.2021 | Desna Chernigov | - | SK Dnipro-1 | 2:1 |  |
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| 5. Journée | 21.08.2021 | SK Dnipro-1 | - | Rukh Lviv | 2:0 | ||||
| 6. Journée | 28.08.2021 | Metalist 1925 Kharkiv | - | SK Dnipro-1 | 1:2 | ||||
| 7. Journée | 11.09.2021 | Shakhtar Donetsk | - | SK Dnipro-1 | 2:0 | ||||
| 11. Journée | 16.10.2021 | SK Dnipro-1 | - | Kolos Kovalivka | 2:0 | ||||
| 12. Journée | 24.10.2021 | Dinamo Kiev | - | SK Dnipro-1 | 2:0 | |
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| 14. Journée | 07.11.2021 | Inhulets Petrove | - | SK Dnipro-1 | 0:1 | ||||
| 15. Journée | 20.11.2021 | SK Dnipro-1 | - | FK Oleksandriya | 3:1 |  |
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| 18. Journée | 10.12.2021 | FK Mariupol | - | SK Dnipro-1 | 0:3 |
Ukraine