| 2. Journée | 25.02.2012 | River Plate | - | Liverpool | 1:3 |  |
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| 3. Journée | 04.03.2012 | Rentistas | - | River Plate | 0:2 | |
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| 4. Journée | 11.03.2012 | River Plate | - | Montevideo Wanderers | 2:2 | ||||
| 5. Journée | 24.03.2012 | Rampla Juniors | - | River Plate | 2:1 | |
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| 6. Journée | 01.04.2012 | River Plate | - | Cerrito | 2:2 | |
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| 8. Journée | 15.04.2012 | River Plate | - | CA Cerro | 3:3 | |
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| 9. Journée | 22.04.2012 | Cerro Largo | - | River Plate | 0:3 | |
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| 10. Journée | 28.04.2012 | River Plate | - | Fénix | 2:1 | ||||
| 7. Journée | 03.05.2012 | Peñarol | - | River Plate | 1:0 | |
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| 11. Journée | 06.05.2012 | Bella Vista | - | River Plate | 0:1 | |
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| 12. Journée | 13.05.2012 | River Plate | - | Danubio | 1:1 | ||||
| 13. Journée | 19.05.2012 | River Plate | - | El Tanque Sisley | 4:0 | |
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| 14. Journée | 28.05.2012 | Racing | - | River Plate | 4:2 | |
Uruguay