| 11. Journée | 17.04.2021 | Sporting San Miguelito | - | Atlético Chiriquí | 2:1 | ||||
| 12. Journée | 21.04.2021 | Sporting San Miguelito | - | Alianza | 0:0 |  |
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| 13. Journée | 25.04.2021 | Plaza Amador | - | Sporting San Miguelito | 2:1 | ||||
| 14. Journée | 28.04.2021 | Sporting San Miguelito | - | Tauro FC | 2:2 | ||||
| 15. Journée | 06.05.2021 | Sporting San Miguelito | - | Deportivo del Este | 1:0 | ||||
| 16. Journée | 09.05.2021 | Árabe Unido | - | Sporting San Miguelito | 1:2 |
Panama