| 1. Journée | 17.01.2021 | Fénix | - | River Plate | 0:3 | ||||
| 2. Journée | 20.01.2021 | River Plate | - | CA Cerro | 1:2 | ||||
| 3. Journée | 01.02.2021 | Defensor Sporting | - | River Plate | 0:2 |  |
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| 4. Journée | 04.02.2021 | River Plate | - | Danubio | 0:4 | ||||
| 12. Journée | 14.03.2021 | Liverpool | - | River Plate | 3:2 |  |
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| 13. Journée | 20.03.2021 | River Plate | - | Montevideo City Torque | 1:1 | |
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| 15. Journée | 29.03.2021 | River Plate | - | Progreso | 3:2 | |
Uruguay
Espagne