| 2. Journée | 21.02.2021 | River Plate | - | Rosario Central | 3:0 |  |
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| 3. Journée | 02.03.2021 | Rosario Central | - | Godoy Cruz | 2:2 | |
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| 4. Journée | 08.03.2021 | Racing Club | - | Rosario Central | 1:0 | ||||
| 5. Journée | 15.03.2021 | Rosario Central | - | Arsenal de Sarandí | 2:1 | |
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| 6. Journée | 21.03.2021 | Colón de Santa Fe | - | Rosario Central | 0:0 | |
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| 7. Journée | 28.03.2021 | Rosario Central | - | Central Córdoba SdE | 2:2 | |
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| 9. Journée | 11.04.2021 | Rosario Central | - | Banfield | 3:1 | |
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| 11. Journée | 26.04.2021 | Rosario Central | - | Estudiantes | 0:1 | |
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| 12. Journée | 03.05.2021 | Rosario Central | - | Newell's Old Boys | 3:0 |
Argentine