| 6. Journée | 20.08.2017 | Orlando City | - | Columbus Crew | 1:1 | ||||
| 6. Journée | 24.08.2017 | Columbus Crew | - | Los Angeles Galaxy | 2:0 |  |
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| 6. Journée | 27.08.2017 | Columbus Crew | - | FC Dallas | 2:1 | ||||
| 7. Journée | 10.09.2017 | Columbus Crew | - | Sporting Kansas City | 1:1 | ||||
| 7. Journée | 17.09.2017 | Vancouver Whitecaps | - | Columbus Crew | 2:2 | ||||
| 7. Journée | 24.09.2017 | Columbus Crew | - | New York RB | 3:2 | |
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| 7. Journée | 01.10.2017 | Columbus Crew | - | D.C. United | 2:0 | ||||
| 8. Journée | 15.10.2017 | Orlando City | - | Columbus Crew | 0:1 | ||||
| 8. Journée | 22.10.2017 | New York City FC | - | Columbus Crew | 2:2 |
Portugal