| 12. Journée | 11.05.2025 | Houston Dynamo | - | Seattle Sounders | 1:3 | ||||
| 13. Journée | 15.05.2025 | Houston Dynamo | - | Minnesota United FC | 2:0 |  |
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| 14. Journée | 18.05.2025 | FC Dallas | - | Houston Dynamo | 0:2 | ||||
| 15. Journée | 25.05.2025 | San Jose Earthquakes | - | Houston Dynamo | 3:3 | |
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| 16. Journée | 29.05.2025 | New York City FC | - | Houston Dynamo | 0:3 |
Colombie