| 2. Journée | 25.08.2021 | SuperSport United | - | Golden Arrows | 3:1 | ||||
| 4. Journée | 19.09.2021 | Moroka Swallows | - | SuperSport United | 0:3 | ||||
| 5. Journée | 25.09.2021 | SuperSport United | - | Maritzburg United | 2:1 | ||||
| 6. Journée | 02.10.2021 | Chippa United | - | SuperSport United | 0:0 | ||||
| 14. Journée | 08.12.2021 | Stellenbosch FC | - | SuperSport United | 0:1 | ||||
| 15. Journée | 11.12.2021 | SuperSport United | - | Mamelodi Sundowns | 0:1 | ||||
| 16. Journée | 18.12.2021 | Sekhukhune United | - | SuperSport United | 0:0 | ||||
| 17. Journée | 22.12.2021 | SuperSport United | - | Cape Town City FC | 3:2 | ||||
| 18. Journée | 15.02.2022 | Maritzburg United | - | SuperSport United | 2:1 | ||||
| 20. Journée | 27.02.2022 | SuperSport United | - | Royal AM | 0:2 | ||||
| 22. Journée | 19.03.2022 | TS Galaxy | - | SuperSport United | 1:1 | ||||
| 24. Journée | 05.04.2022 | SuperSport United | - | Chippa United | 1:1 | ||||
| 27. Journée | 03.05.2022 | SuperSport United | - | Stellenbosch FC | 0:0 | ||||
| 29. Journée | 14.05.2022 | Baroka FC | - | SuperSport United | 3:1 |
Ouganda