| 1. Journée | 05.03.2022 | Anorthosis Famagusta | - | AEK Larnaca | 1:3 |  |
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| 3. Journée | 19.03.2022 | Paphos FC | - | Anorthosis Famagusta | 2:2 | ||||
| 4. Journée | 02.04.2022 | Anorthosis Famagusta | - | APOEL Nikosia | 4:1 | ||||
| 5. Journée | 10.04.2022 | Aris Limassol | - | Anorthosis Famagusta | 1:1 |  |
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| 6. Journée | 18.04.2022 | AEK Larnaca | - | Anorthosis Famagusta | 1:0 | ||||
| 7. Journée | 30.04.2022 | Anorthosis Famagusta | - | Apollon Limassol | 1:1 | |
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| 8. Journée | 09.05.2022 | Anorthosis Famagusta | - | Paphos FC | 1:0 | ||||
| 9. Journée | 15.05.2022 | APOEL Nikosia | - | Anorthosis Famagusta | 1:1 | ||||
| 10. Journée | 21.05.2022 | Anorthosis Famagusta | - | Aris Limassol | 0:3 |
Chypre