| 1. Journée | 09.08.2021 | Honduras Progreso | - | Marathón | 1:2 | ||||
| 4. Journée | 22.08.2021 | Honduras Progreso | - | Victoria | 2:0 | ||||
| 5. Journée | 26.08.2021 | Olimpia | - | Honduras Progreso | 2:1 | ||||
| 6. Journée | 29.08.2021 | Honduras Progreso | - | Vida | 1:1 | ||||
| 7. Journée | 05.09.2021 | Honduras Progreso | - | Motagua | 0:3 | ||||
| 8. Journée | 12.09.2021 | Real Sociedad | - | Honduras Progreso | 1:0 | ||||
| 9. Journée | 16.09.2021 | Honduras Progreso | - | Real España | 1:1 | ||||
| 10. Journée | 20.09.2021 | Vida | - | Honduras Progreso | 1:0 | ||||
| 11. Journée | 23.09.2021 | Victoria | - | Honduras Progreso | 1:2 | ||||
| 15. Journée | 24.10.2021 | Honduras Progreso | - | Olimpia | 0:2 | ||||
| 16. Journée | 28.10.2021 | Real España | - | Honduras Progreso | 4:1 | ||||
| 17. Journée | 01.11.2021 | Honduras Progreso | - | Real Sociedad | 2:1 | ||||
| 18. Journée | 10.11.2021 | Motagua | - | Honduras Progreso | 3:2 |
Honduras