| 4. Journée | 15.10.2020 | Lobos UPNFM | - | Real de Minas | 2:2 | ||||
| 5. Journée | 19.10.2020 | Honduras Progreso | - | Lobos UPNFM | 2:3 | ||||
| 7. Journée | 24.10.2020 | Lobos UPNFM | - | Real Sociedad | 1:1 |  |
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| 8. Journée | 29.10.2020 | Lobos UPNFM | - | Olimpia | 1:1 | |
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| 9. Journée | 01.11.2020 | Real de Minas | - | Lobos UPNFM | 1:1 | |
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| 10. Journée | 23.11.2020 | Lobos UPNFM | - | Honduras Progreso | 0:1 | ||||
| 11. Journée | 26.11.2020 | Lobos UPNFM | - | Marathón | 0:2 | |
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| 12. Journée | 30.11.2020 | Platense | - | Lobos UPNFM | 1:1 | |
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| 6. Journée | 06.12.2020 | Motagua | - | Lobos UPNFM | 0:1 | ||||
| 14. Journée | 12.12.2020 | Vida | - | Lobos UPNFM | 0:3 | |
Honduras