| 1. Journée | 21.07.2018 | Boston River | - | River Plate | 2:3 |  |
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| 5. Journée | 19.08.2018 | Torque | - | River Plate | 3:0 | ||||
| 6. Journée | 26.08.2018 | River Plate | - | Rampla Juniors | 3:4 | ||||
| 7. Journée | 01.09.2018 | Fénix | - | River Plate | 1:3 | ||||
| 8. Journée | 09.09.2018 | River Plate | - | Nacional | 0:0 | ||||
| 10. Journée | 23.09.2018 | River Plate | - | Defensor Sporting | 3:2 | ||||
| 13. Journée | 21.10.2018 | River Plate | - | Montevideo Wanderers | 0:5 |
Uruguay