| 1. Journée | 19.08.2023 | Fénix | - | Defensor Sporting | 1:1 | ||||
| 2. Journée | 25.08.2023 | Defensor Sporting | - | Montevideo Wanderers | 3:0 |  |
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| 3. Journée | 03.09.2023 | La Luz | - | Defensor Sporting | 1:1 | |
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| 4. Journée | 07.10.2023 | Peñarol | - | Defensor Sporting | 2:1 | ||||
| 5. Journée | 13.10.2023 | Defensor Sporting | - | Montevideo City Torque | 2:0 | ||||
| 6. Journée | 18.10.2023 | Liverpool | - | Defensor Sporting | 2:0 | ||||
| 7. Journée | 22.10.2023 | Defensor Sporting | - | Cerro Largo | 2:0 | ||||
| 8. Journée | 05.11.2023 | Plaza Colonia | - | Defensor Sporting | 0:2 | ||||
| 9. Journée | 11.11.2023 | Defensor Sporting | - | Racing | 3:0 | ||||
| 10. Journée | 15.11.2023 | CA Cerro | - | Defensor Sporting | 1:1 | ||||
| 11. Journée | 20.11.2023 | Defensor Sporting | - | Boston River | 2:0 | |
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| 12. Journée | 25.11.2023 | Deportivo Maldonado | - | Defensor Sporting | 2:1 | |
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| 13. Journée | 30.11.2023 | Defensor Sporting | - | River Plate | 0:1 | ||||
| 14. Journée | 05.12.2023 | Nacional | - | Defensor Sporting | 1:0 | ||||
| 15. Journée | 07.12.2023 | Defensor Sporting | - | Danubio | 0:2 |  |
Uruguay