| 1. Journée | 09.07.2016 | Libertad | - | River Plate | 1:1 | ||||
| 2. Journée | 17.07.2016 | River Plate | - | General Díaz | 0:0 | ||||
| 3. Journée | 20.07.2016 | Guaraní | - | River Plate | 2:0 | ||||
| 4. Journée | 25.07.2016 | River Plate | - | Club Olimpia | 0:2 | ||||
| 5. Journée | 02.08.2016 | Club Rubio Ñu | - | River Plate | 5:1 | ||||
| 6. Journée | 07.08.2016 | River Plate | - | General Caballero ZC | 1:1 |  |
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| 7. Journée | 12.08.2016 | Sportivo Luqueño | - | River Plate | 1:0 | ||||
| 8. Journée | 20.08.2016 | Deportivo Capiatá | - | River Plate | 0:3 | ||||
| 9. Journée | 29.08.2016 | River Plate | - | Cerro Porteño | 2:3 | ||||
| 10. Journée | 10.09.2016 | Sol de América | - | River Plate | 2:6 | ||||
| 11. Journée | 18.09.2016 | River Plate | - | Club Nacional | 2:3 | ||||
| 12. Journée | 24.09.2016 | River Plate | - | Libertad | 2:0 | ||||
| 13. Journée | 30.09.2016 | General Díaz | - | River Plate | 2:0 | ||||
| 14. Journée | 17.10.2016 | River Plate | - | Guaraní | 0:2 | ||||
| 15. Journée | 23.10.2016 | Club Olimpia | - | River Plate | 5:3 | ||||
| 17. Journée | 05.11.2016 | General Caballero ZC | - | River Plate | 1:0 |
Paraguay