| 1. Journée | 17.05.2021 | Cerrito | - | River Plate | 3:1 | ||||
| 2. Journée | 24.05.2021 | River Plate | - | Liverpool | 3:2 | ||||
| 5. Journée | 12.06.2021 | River Plate | - | Progreso | 4:0 |  |
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| 6. Journée | 19.06.2021 | Sud América | - | River Plate | 1:2 | ||||
| 7. Journée | 22.06.2021 | River Plate | - | Plaza Colonia | 0:1 | ||||
| 8. Journée | 26.06.2021 | Fénix | - | River Plate | 3:4 | ||||
| 9. Journée | 03.07.2021 | River Plate | - | Boston River | 1:1 | ||||
| 10. Journée | 10.07.2021 | Montevideo Wanderers | - | River Plate | 1:2 | ||||
| 11. Journée | 17.07.2021 | River Plate | - | Rentistas | 0:0 | ||||
| 13. Journée | 07.08.2021 | River Plate | - | Montevideo City Torque | 3:3 | ||||
| 14. Journée | 15.08.2021 | Villa Española | - | River Plate | 1:1 |
Uruguay
Espagne