| 3. Journée | 22.03.2025 | Louisville City FC | - | Loudoun United | 2:0 | ||||
| 4. Journée | 29.03.2025 | Louisville City FC | - | Detroit City FC | 2:0 | ||||
| 5. Journée | 06.04.2025 | Sacramento Republic | - | Louisville City FC | 1:1 | ||||
| 7. Journée | 20.04.2025 | Tampa Bay Rowdies | - | Louisville City FC | 1:2 | ||||
| 8. Journée | 02.05.2025 | Louisville City FC | - | Lexington SC | 2:0 | ||||
| 9. Journée | 11.05.2025 | Louisville City FC | - | Pittsburgh Riverhounds | 0:0 | ||||
| 10. Journée | 18.05.2025 | Hartford Athletic | - | Louisville City FC | 1:1 | ||||
| 11. Journée | 25.05.2025 | Monterey Bay FC | - | Louisville City FC | 0:2 | ||||
| 12. Journée | 08.06.2025 | Louisville City FC | - | Tampa Bay Rowdies | 2:1 | ||||
| 13. Journée | 12.06.2025 | Louisville City FC | - | Rhode Island FC | 2:1 |  |
|||
| 13. Journée | 15.06.2025 | Louisville City FC | - | Birmingham Legion | 4:2 | ||||
| 14. Journée | 21.06.2025 | North Carolina FC | - | Louisville City FC | 2:1 |
États-Unis