| 1. Journée | 27.03.2010 | Columbus Crew | - | Toronto FC | 2:0 | ||||
| 2. Journée | 25.04.2010 | Columbus Crew | - | Real Salt Lake | 1:0 | ||||
| 3. Journée | 02.05.2010 | Seattle Sounders | - | Columbus Crew | 1:1 | ||||
| 3. Journée | 09.05.2010 | Columbus Crew | - | New England Revolution | 3:2 | ||||
| 3. Journée | 16.05.2010 | Columbus Crew | - | CD Chivas | 1:0 | ||||
| 3. Journée | 21.05.2010 | New York RB | - | Columbus Crew | 1:3 | ||||
| 3. Journée | 23.05.2010 | Kansas City Wizards | - | Columbus Crew | 0:1 | ||||
| 4. Journée | 03.06.2010 | San Jose Earthquakes | - | Columbus Crew | 2:2 |  |
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| 4. Journée | 06.06.2010 | Colorado Rapids | - | Columbus Crew | 1:0 | ||||
| 4. Journée | 27.06.2010 | Columbus Crew | - | D.C. United | 2:0 |  |
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| 6. Journée | 15.08.2010 | Real Salt Lake | - | Columbus Crew | 2:0 | ||||
| 7. Journée | 26.09.2010 | New England Revolution | - | Columbus Crew | 2:2 | ||||
| 8. Journée | 09.10.2010 | Chicago Fire | - | Columbus Crew | 2:0 | |
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| 8. Journée | 24.10.2010 | Columbus Crew | - | Philadelphia Union | 3:1 |
États-Unis