| 3. Journée | 17.02.2018 | Liverpool | - | Boston River | 2:2 | ||||
| 6. Journée | 10.03.2018 | Peñarol | - | Boston River | 2:1 | ||||
| 7. Journée | 21.03.2018 | Boston River | - | Atenas | 1:0 | ||||
| 8. Journée | 24.03.2018 | Danubio | - | Boston River | 0:0 |  |
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| 9. Journée | 28.03.2018 | Boston River | - | Torque | 1:1 | ||||
| 10. Journée | 31.03.2018 | Rampla Juniors | - | Boston River | 0:0 | ||||
| 11. Journée | 06.04.2018 | Boston River | - | Fénix | 0:3 | ||||
| 12. Journée | 15.04.2018 | Nacional | - | Boston River | 1:0 | ||||
| 13. Journée | 22.04.2018 | Boston River | - | Progreso | 3:2 |
Uruguay