| 2. Journée | 07.08.2022 | Lobos UPNFM | - | Real Sociedad | 2:0 | ||||
| 3. Journée | 11.08.2022 | Victoria | - | Lobos UPNFM | 4:0 | ||||
| 6. Journée | 29.08.2022 | Olimpia | - | Lobos UPNFM | 2:0 | ||||
| 8. Journée | 04.09.2022 | Marathón | - | Lobos UPNFM | 1:1 | ||||
| 9. Journée | 11.09.2022 | Vida | - | Lobos UPNFM | 2:1 |  |
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| 10. Journée | 19.09.2022 | Lobos UPNFM | - | Real España | 2:2 | ||||
| 11. Journée | 02.10.2022 | Real Sociedad | - | Lobos UPNFM | 0:2 | |
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| 14. Journée | 21.10.2022 | Motagua | - | Lobos UPNFM | 2:2 |  |
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| 15. Journée | 24.10.2022 | Lobos UPNFM | - | Olimpia | 0:0 | ||||
| 18. Journée | 19.11.2022 | Lobos UPNFM | - | Vida | 3:2 |
Honduras