| 1. Journée | 22.08.2021 | AS Roma | - | ACF Fiorentina | 3:1 | ||||
| 2. Journée | 29.08.2021 | US Salernitana 1919 | - | AS Roma | 0:4 |  |
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| 3. Journée | 12.09.2021 | AS Roma | - | Sassuolo Calcio | 2:1 | ||||
| 4. Journée | 19.09.2021 | Hellas Verona | - | AS Roma | 3:2 | ||||
| 6. Journée | 26.09.2021 | Lazio Roma | - | AS Roma | 3:2 | ||||
| 11. Journée | 31.10.2021 | AS Roma | - | AC Milan | 1:2 | ||||
| 12. Journée | 07.11.2021 | Venezia FC | - | AS Roma | 3:2 | ||||
| 14. Journée | 28.11.2021 | AS Roma | - | Torino FC | 1:0 | ||||
| 15. Journée | 01.12.2021 | Bologna FC | - | AS Roma | 1:0 | |
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| 20. Journée | 06.01.2022 | AC Milan | - | AS Roma | 3:1 | ||||
| 21. Journée | 09.01.2022 | AS Roma | - | Juventus | 3:4 | ||||
| 25. Journée | 13.02.2022 | Sassuolo Calcio | - | AS Roma | 2:2 | ||||
| 29. Journée | 13.03.2022 | Udinese Calcio | - | AS Roma | 1:1 | ||||
| 32. Journée | 10.04.2022 | AS Roma | - | US Salernitana 1919 | 2:1 |  |
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| 33. Journée | 18.04.2022 | SSC Napoli | - | AS Roma | 1:1 | ||||
| 34. Journée | 23.04.2022 | Inter | - | AS Roma | 3:1 | ||||
| 35. Journée | 01.05.2022 | AS Roma | - | Bologna FC | 0:0 | ||||
| 36. Journée | 09.05.2022 | ACF Fiorentina | - | AS Roma | 2:0 | ||||
| 37. Journée | 14.05.2022 | AS Roma | - | Venezia FC | 1:1 |
Espagne
