| 5. Journée | 26.07.2010 | Seattle Sounders | - | Colorado Rapids | 2:1 | ||||
| 6. Journée | 01.08.2010 | San Jose Earthquakes | - | Seattle Sounders | 0:1 | ||||
| 6. Journée | 09.08.2010 | Seattle Sounders | - | Houston Dynamo | 2:0 |  |
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| 6. Journée | 15.08.2010 | CD Chivas | - | Seattle Sounders | 0:0 | ||||
| 6. Journée | 29.08.2010 | Seattle Sounders | - | Chicago Fire | 2:1 | |
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| 7. Journée | 19.09.2010 | Columbus Crew | - | Seattle Sounders | 0:4 |  |
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| 7. Journée | 26.09.2010 | Chicago Fire | - | Seattle Sounders | 0:1 | |
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| 8. Journée | 02.10.2010 | Seattle Sounders | - | Toronto FC | 3:2 | |
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| 8. Journée | 10.10.2010 | Kansas City Wizards | - | Seattle Sounders | 1:2 | ||||
| 8. Journée | 16.10.2010 | Seattle Sounders | - | CD Chivas | 2:1 | ||||
| 8. Journée | 23.10.2010 | Houston Dynamo | - | Seattle Sounders | 2:1 |
RD Congo