| 2. Journée | 29.08.2010 | Defensor Sporting | - | Liverpool | 3:0 | ||||
| 6. Journée | 02.10.2010 | Defensor Sporting | - | Bella Vista | 1:2 | ||||
| 3. Journée | 06.10.2010 | Defensor Sporting | - | CA Cerro | 2:0 |  |
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| 9. Journée | 24.10.2010 | Defensor Sporting | - | Rampla Juniors | 4:1 |  |
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| 10. Journée | 31.10.2010 | Defensor Sporting | - | Fénix | 5:1 | ||||
| 11. Journée | 06.11.2010 | Racing | - | Defensor Sporting | 0:3 | |
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| 14. Journée | 27.11.2010 | Defensor Sporting | - | Nacional | 1:2 |
Uruguay
Italie