| 4. Journée | 05.09.2015 | Montevideo Wanderers | - | River Plate | 5:1 | ||||
| 5. Journée | 13.09.2015 | River Plate | - | Racing | 3:1 | ||||
| 6. Journée | 20.09.2015 | Plaza Colonia | - | River Plate | 3:2 | ||||
| 7. Journée | 27.09.2015 | River Plate | - | Peñarol | 4:0 | ||||
| 8. Journée | 04.10.2015 | Juventud de Las Piedras | - | River Plate | 2:3 | ||||
| 9. Journée | 18.10.2015 | River Plate | - | Danubio | 2:1 | ||||
| 10. Journée | 25.10.2015 | CA Cerro | - | River Plate | 1:1 | ||||
| 11. Journée | 01.11.2015 | River Plate | - | Rentistas | 2:3 | ||||
| 12. Journée | 07.11.2015 | El Tanque Sisley | - | River Plate | 2:1 | ||||
| 13. Journée | 21.11.2015 | River Plate | - | Liverpool | 2:2 | ||||
| 14. Journée | 28.11.2015 | Defensor Sporting | - | River Plate | 1:2 | ||||
| 15. Journée | 05.12.2015 | River Plate | - | Villa Teresa | 4:0 |
Uruguay