| Zona B | 21.02.2021 | Deportivo Guastatoya | - | Sanarate | 5:1 | ||||
| Zona B | 06.03.2021 | Cobán Imperial | - | Sanarate | 2:0 |  |
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| Zona B | 10.03.2021 | Sanarate | - | Achuapa | 2:1 | ||||
| Zona B | 14.03.2021 | Sanarate | - | Deportivo Guastatoya | 3:2 | ||||
| Zona B | 01.04.2021 | Sacachispas | - | Sanarate | 2:1 | ||||
| Zona B | 07.04.2021 | Sanarate | - | Cobán Imperial | 0:0 | ||||
| Zona B | 11.04.2021 | Achuapa | - | Sanarate | 2:2 | ||||
| Demi-finales Groupe A | 14.04.2021 | Sanarate | - | Antigua GFC | 1:1 | ||||
| Demi-finales Groupe A | 24.04.2021 | Santa Lucía | - | Sanarate | 1:0 | ||||
| Demi-finales Groupe A | 28.04.2021 | Sanarate | - | Xelaju MC | 1:1 |
Guatemala