| 1. Journée | 09.02.2022 | Cerrito | - | Danubio | 0:1 |  |
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| 2. Journée | 13.02.2022 | Boston River | - | Cerrito | 0:1 | ||||
| 3. Journée | 21.02.2022 | Cerrito | - | Deportivo Maldonado | 0:3 | ||||
| 4. Journée | 28.02.2022 | River Plate | - | Cerrito | 3:1 | |
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| 6. Journée | 22.03.2022 | Cerro Largo | - | Cerrito | 1:0 | ||||
| 9. Journée | 17.04.2022 | Cerrito | - | Peñarol | 0:0 | |
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| 10. Journée | 26.04.2022 | Defensor Sporting | - | Cerrito | 0:0 | ||||
| 11. Journée | 07.05.2022 | Cerrito | - | Montevideo City Torque | 2:2 | ||||
| 12. Journée | 15.05.2022 | Albion | - | Cerrito | 2:2 |  |
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| 13. Journée | 22.05.2022 | Cerrito | - | Montevideo Wanderers | 0:2 | |
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| 15. Journée | 04.06.2022 | Cerrito | - | Plaza Colonia | 1:1 |
Uruguay