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| Classement | équipe recevante | à l'extérieur | Premier tour | Second tour | 1. Mi-temps | » 2. Mi-temps |
| 1 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Columbus Crew (M) | 34 | 19 | 9 | 6 | 47:26 | 21 | 66 |
| 2 |
|
Inter Miami CF | 34 | 17 | 11 | 6 | 46:25 | 21 | 62 |
| 3 |
|
FC Cincinnati | 34 | 15 | 13 | 6 | 38:26 | 12 | 58 |
| 4 |
|
Orlando City | 34 | 15 | 11 | 8 | 34:25 | 9 | 56 |
| 5 |
|
Philadelphia Union | 34 | 14 | 9 | 11 | 34:32 | 2 | 51 |
| 6 |
|
New York RB | 34 | 13 | 11 | 10 | 34:29 | 5 | 50 |
| 7 |
|
Atlanta United FC | 34 | 12 | 11 | 11 | 31:31 | 0 | 47 |
| 8 |
|
Charlotte FC | 34 | 11 | 14 | 9 | 27:21 | 6 | 47 |
| 9 |
|
Chicago Fire | 34 | 12 | 8 | 14 | 29:31 | -2 | 44 |
| 10 |
|
CF Montréal | 34 | 10 | 10 | 14 | 26:33 | -7 | 40 |
| 11 |
|
New York City FC | 34 | 10 | 8 | 16 | 24:30 | -6 | 38 |
| 12 |
|
D.C. United | 34 | 10 | 6 | 18 | 25:38 | -13 | 36 |
| 13 |
|
Toronto FC | 34 | 9 | 7 | 18 | 23:45 | -22 | 34 |
| 14 |
|
Nashville SC | 34 | 8 | 10 | 16 | 18:27 | -9 | 34 |
| 15 |
|
New England Revolution | 34 | 5 | 5 | 24 | 15:47 | -32 | 20 |
| 2 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Los Angeles Galaxy | 34 | 15 | 15 | 4 | 47:24 | 23 | 60 |
| 2 |
|
Los Angeles FC | 34 | 16 | 9 | 9 | 33:25 | 8 | 57 |
| 3 |
|
Colorado Rapids | 34 | 16 | 6 | 12 | 35:32 | 3 | 54 |
| 4 |
|
Seattle Sounders | 34 | 14 | 10 | 10 | 28:19 | 9 | 52 |
| 5 |
|
Portland Timbers | 34 | 14 | 9 | 11 | 38:28 | 10 | 51 |
| 6 |
|
Minnesota United FC | 34 | 13 | 12 | 9 | 33:25 | 8 | 51 |
| 7 |
|
Vancouver Whitecaps | 34 | 13 | 12 | 9 | 31:25 | 6 | 51 |
| 8 |
|
Real Salt Lake | 34 | 11 | 15 | 8 | 35:29 | 6 | 48 |
| 9 |
|
Houston Dynamo | 34 | 9 | 14 | 11 | 27:28 | -1 | 41 |
| 10 |
|
Austin FC | 34 | 9 | 13 | 12 | 24:27 | -3 | 40 |
| 11 |
|
FC Dallas | 34 | 9 | 12 | 13 | 31:33 | -2 | 39 |
| 12 |
|
Sporting Kansas City | 34 | 9 | 12 | 13 | 32:39 | -7 | 39 |
| 13 |
|
St. Louis City SC | 34 | 8 | 11 | 15 | 24:40 | -16 | 35 |
| 14 |
|
San Jose Earthquakes | 34 | 7 | 7 | 20 | 20:49 | -29 | 28 |
| Play-off | |
| Play-off |
