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| Classement | équipe recevante | à l'extérieur | Premier tour | Second tour | 1. Mi-temps | » 2. Mi-temps |
| 1 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Columbus Crew (M) | 31 | 18 | 8 | 5 | 43:22 | 21 | 62 |
| 2 |
|
Inter Miami CF | 31 | 15 | 11 | 5 | 40:23 | 17 | 56 |
| 3 |
|
FC Cincinnati | 31 | 14 | 12 | 5 | 35:22 | 13 | 54 |
| 4 |
|
Philadelphia Union | 31 | 14 | 8 | 9 | 32:28 | 4 | 50 |
| 5 |
|
Orlando City | 31 | 13 | 10 | 8 | 30:24 | 6 | 49 |
| 6 |
|
New York RB | 31 | 11 | 11 | 9 | 28:25 | 3 | 44 |
| 7 |
|
Atlanta United FC | 31 | 11 | 10 | 10 | 29:29 | 0 | 43 |
| 8 |
|
Chicago Fire | 32 | 11 | 8 | 13 | 27:27 | 0 | 41 |
| 9 |
|
Charlotte FC | 31 | 9 | 14 | 8 | 22:19 | 3 | 41 |
| 10 |
|
New York City FC | 31 | 10 | 6 | 15 | 22:27 | -5 | 36 |
| 11 |
|
CF Montréal | 31 | 9 | 9 | 13 | 25:32 | -7 | 36 |
| 12 |
|
Toronto FC | 32 | 9 | 7 | 16 | 22:41 | -19 | 34 |
| 13 |
|
D.C. United | 31 | 9 | 6 | 16 | 22:33 | -11 | 33 |
| 14 |
|
Nashville SC | 31 | 6 | 10 | 15 | 13:24 | -11 | 28 |
| 15 |
|
New England Revolution | 31 | 4 | 5 | 22 | 13:41 | -28 | 17 |
| 2 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Los Angeles Galaxy | 31 | 14 | 13 | 4 | 42:22 | 20 | 55 |
| 2 |
|
Colorado Rapids | 31 | 16 | 6 | 9 | 34:26 | 8 | 54 |
| 3 |
|
Los Angeles FC | 31 | 14 | 8 | 9 | 29:25 | 4 | 50 |
| 4 |
|
Vancouver Whitecaps | 31 | 13 | 11 | 7 | 30:21 | 9 | 50 |
| 5 |
|
Portland Timbers | 31 | 13 | 7 | 11 | 37:28 | 9 | 46 |
| 6 |
|
Seattle Sounders | 31 | 12 | 10 | 9 | 25:18 | 7 | 46 |
| 7 |
|
Minnesota United FC | 31 | 12 | 10 | 9 | 30:24 | 6 | 46 |
| 8 |
|
Real Salt Lake | 31 | 9 | 14 | 8 | 32:28 | 4 | 41 |
| 9 |
|
FC Dallas | 31 | 9 | 11 | 11 | 30:30 | 0 | 38 |
| 10 |
|
Houston Dynamo | 31 | 8 | 13 | 10 | 24:24 | 0 | 37 |
| 11 |
|
Sporting Kansas City | 32 | 8 | 12 | 12 | 31:38 | -7 | 36 |
| 12 |
|
Austin FC | 31 | 8 | 11 | 12 | 21:25 | -4 | 35 |
| 13 |
|
St. Louis City SC | 31 | 7 | 10 | 14 | 21:37 | -16 | 31 |
| 14 |
|
San Jose Earthquakes | 31 | 6 | 7 | 18 | 18:44 | -26 | 25 |
| Play-off | |
| Play-off |
