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| Classement | équipe recevante | à l'extérieur | Premier tour | Second tour | » 1. Mi-temps | 2. Mi-temps |
| 1 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Columbus Crew (M) | 31 | 13 | 12 | 6 | 21:11 | 10 | 51 |
| 2 |
|
Inter Miami CF | 31 | 12 | 12 | 7 | 29:22 | 7 | 48 |
| 3 |
|
New York RB | 31 | 12 | 12 | 7 | 20:19 | 1 | 48 |
| 4 |
|
Philadelphia Union | 31 | 13 | 8 | 10 | 26:20 | 6 | 47 |
| 5 |
|
New York City FC | 31 | 11 | 13 | 7 | 26:17 | 9 | 46 |
| 6 |
|
Nashville SC | 31 | 12 | 8 | 11 | 18:23 | -5 | 44 |
| 7 |
|
Toronto FC | 32 | 10 | 12 | 10 | 17:15 | 2 | 42 |
| 8 |
|
Orlando City | 31 | 11 | 7 | 13 | 23:22 | 1 | 40 |
| 9 |
|
D.C. United | 31 | 10 | 9 | 12 | 24:30 | -6 | 39 |
| 10 |
|
FC Cincinnati | 31 | 8 | 14 | 9 | 18:19 | -1 | 38 |
| 11 |
|
New England Revolution | 31 | 9 | 10 | 12 | 20:23 | -3 | 37 |
| 12 |
|
Charlotte FC | 31 | 6 | 19 | 6 | 15:15 | 0 | 37 |
| 13 |
|
CF Montréal | 31 | 8 | 11 | 12 | 19:29 | -10 | 35 |
| 14 |
|
Atlanta United FC | 31 | 6 | 15 | 10 | 12:16 | -4 | 33 |
| 15 |
|
Chicago Fire | 32 | 4 | 12 | 16 | 10:28 | -18 | 24 |
| 2 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Los Angeles FC | 31 | 14 | 7 | 10 | 27:17 | 10 | 49 |
| 2 |
|
Houston Dynamo | 31 | 11 | 15 | 5 | 19:10 | 9 | 48 |
| 3 |
|
Real Salt Lake | 31 | 12 | 11 | 8 | 30:19 | 11 | 47 |
| 4 |
|
Seattle Sounders | 31 | 12 | 11 | 8 | 21:16 | 5 | 47 |
| 5 |
|
Portland Timbers | 31 | 12 | 8 | 11 | 27:26 | 1 | 44 |
| 6 |
|
St. Louis City SC | 31 | 11 | 11 | 9 | 25:21 | 4 | 44 |
| 7 |
|
Vancouver Whitecaps | 31 | 11 | 9 | 11 | 21:22 | -1 | 42 |
| 8 |
|
Minnesota United FC | 31 | 11 | 8 | 12 | 23:24 | -1 | 41 |
| 9 |
|
Colorado Rapids | 31 | 10 | 11 | 10 | 24:27 | -3 | 41 |
| 10 |
|
Los Angeles Galaxy | 31 | 10 | 11 | 10 | 21:24 | -3 | 41 |
| 11 |
|
FC Dallas | 31 | 7 | 15 | 9 | 20:22 | -2 | 36 |
| 12 |
|
Sporting Kansas City | 32 | 8 | 11 | 13 | 19:23 | -4 | 35 |
| 13 |
|
Austin FC | 31 | 7 | 14 | 10 | 13:19 | -6 | 35 |
| 14 |
|
San Jose Earthquakes | 31 | 6 | 12 | 13 | 19:28 | -9 | 30 |
| Play-off | |
| Play-off |
