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| Classement | équipe recevante | à l'extérieur | Premier tour | Second tour | » 1. Mi-temps | 2. Mi-temps |
| 1 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Columbus Crew (M) | 27 | 12 | 10 | 5 | 20:10 | 10 | 46 |
| 2 |
|
New York RB | 27 | 12 | 10 | 5 | 18:13 | 5 | 46 |
| 3 |
|
Philadelphia Union | 27 | 11 | 7 | 9 | 20:17 | 3 | 40 |
| 4 |
|
Inter Miami CF | 27 | 10 | 10 | 7 | 26:21 | 5 | 40 |
| 5 |
|
New York City FC | 27 | 9 | 12 | 6 | 20:13 | 7 | 39 |
| 6 |
|
Nashville SC | 27 | 9 | 7 | 11 | 14:22 | -8 | 34 |
| 7 |
|
Toronto FC | 28 | 8 | 10 | 10 | 14:15 | -1 | 34 |
| 8 |
|
FC Cincinnati | 27 | 7 | 13 | 7 | 15:16 | -1 | 34 |
| 9 |
|
Orlando City | 27 | 9 | 6 | 12 | 20:21 | -1 | 33 |
| 10 |
|
D.C. United | 27 | 8 | 9 | 10 | 21:27 | -6 | 33 |
| 11 |
|
Charlotte FC | 27 | 5 | 17 | 5 | 13:13 | 0 | 32 |
| 12 |
|
Atlanta United FC | 27 | 6 | 13 | 8 | 11:13 | -2 | 31 |
| 13 |
|
New England Revolution | 26 | 7 | 9 | 10 | 16:19 | -3 | 30 |
| 14 |
|
CF Montréal | 27 | 6 | 10 | 11 | 16:26 | -10 | 28 |
| 15 |
|
Chicago Fire | 27 | 3 | 12 | 12 | 9:23 | -14 | 21 |
| 2 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Los Angeles FC | 27 | 12 | 7 | 8 | 24:15 | 9 | 43 |
| 2 |
|
Houston Dynamo | 27 | 9 | 14 | 4 | 16:9 | 7 | 41 |
| 3 |
|
Real Salt Lake | 27 | 10 | 10 | 7 | 26:16 | 10 | 40 |
| 4 |
|
Portland Timbers | 27 | 11 | 6 | 10 | 23:21 | 2 | 39 |
| 5 |
|
Colorado Rapids | 27 | 10 | 9 | 8 | 23:24 | -1 | 39 |
| 6 |
|
Vancouver Whitecaps | 27 | 10 | 8 | 9 | 19:19 | 0 | 38 |
| 7 |
|
Seattle Sounders | 28 | 9 | 11 | 8 | 16:15 | 1 | 38 |
| 8 |
|
Los Angeles Galaxy | 28 | 9 | 11 | 8 | 19:20 | -1 | 38 |
| 9 |
|
St. Louis City SC | 27 | 9 | 10 | 8 | 20:17 | 3 | 37 |
| 10 |
|
Minnesota United FC | 27 | 10 | 6 | 11 | 21:21 | 0 | 36 |
| 11 |
|
FC Dallas | 28 | 6 | 15 | 7 | 18:19 | -1 | 33 |
| 12 |
|
Sporting Kansas City | 27 | 7 | 9 | 11 | 18:20 | -2 | 30 |
| 13 |
|
Austin FC | 27 | 6 | 12 | 9 | 12:17 | -5 | 30 |
| 14 |
|
San Jose Earthquakes | 27 | 6 | 11 | 10 | 17:23 | -6 | 29 |
| Play-off | |
| Play-off |
