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| H (Match allé) | Inter Playa | - | Chihuahua FC | 1:1 (1:1) | ||
| R (match retour) | Chihuahua FC | - | Inter Playa | 0:2 (0:1) | ||
| H (Match allé): 08.04.2023 01:00 | R (match retour): 15.04.2023 04:00 | vainqueur: Inter Playa | ||||
| H (Match allé) | Cafetaleros de Chiapas | - | Tampico Madero | 1:0 (0:0) | ||
| R (match retour) | Tampico Madero | - | Cafetaleros de Chiapas | 2:0 (0:0) | ||
| H (Match allé): 10.04.2023 02:00 | R (match retour): 16.04.2023 04:00 | vainqueur: Tampico Madero | ||||
