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| 22.10.2022 | 17:00 | Mazatlán FC | - | CF Monterrey | 0:4 (0:1) | |
| 18:00 | UANL Tigres | - | Club León | 3:1 (2:0) | ||
| 18:30 | Club Necaxa | - | Cruz Azul | 3:0 (3:0) | ||
| 18:30 | Pumas UNAM | - | Puebla FC | 1:0 (0:0) | ||
| 18:30 | Deportivo Toluca | - | Gallos Blancos | 1:0 (1:0) | ||
| 18:30 | Santos Laguna | - | Club Tijuana | 1:0 (1:0) | ||
| 18:30 | Atlas Guadalajara | - | Deportivo Guadalajara | 1:0 (1:0) | ||
| 23.10.2022 | 16:30 | CF Pachuca | - | CF América | 2:1 (2:1) |
| » Classement | Premier tour | Second tour |
| 1 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pumas UNAM | 16 | 12 | 2 | 2 | 39:17 | 22 | 38 |
| 2 |
|
Club Necaxa | 16 | 9 | 3 | 4 | 34:12 | 22 | 30 |
| 3 |
|
Deportivo Toluca | 16 | 9 | 3 | 4 | 32:20 | 12 | 30 |
| 4 |
|
CF Pachuca | 16 | 6 | 8 | 2 | 26:17 | 9 | 26 |
| 5 |
|
CF América | 16 | 7 | 3 | 6 | 30:28 | 2 | 24 |
| 6 |
|
Cruz Azul | 16 | 4 | 5 | 7 | 24:30 | -6 | 17 |
| 7 |
|
Gallos Blancos | 16 | 3 | 5 | 8 | 18:22 | -4 | 14 |
| 8 |
|
FC Juárez | 16 | 3 | 2 | 11 | 19:58 | -39 | 11 |
| 9 |
|
Puebla FC | 16 | 2 | 3 | 11 | 18:36 | -18 | 9 |
| 2 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Tijuana | 16 | 10 | 2 | 4 | 41:16 | 25 | 32 |
| 2 |
|
CF Monterrey | 16 | 8 | 7 | 1 | 42:22 | 20 | 31 |
| 3 |
|
Deportivo Guadalajara | 16 | 9 | 2 | 5 | 34:19 | 15 | 29 |
| 4 |
|
Santos Laguna | 16 | 8 | 4 | 4 | 36:22 | 14 | 28 |
| 5 |
|
UANL Tigres | 16 | 8 | 3 | 5 | 29:31 | -2 | 27 |
| 6 |
|
Atlas Guadalajara | 16 | 7 | 3 | 6 | 31:24 | 7 | 24 |
| 7 |
|
Club León | 16 | 6 | 3 | 7 | 27:24 | 3 | 21 |
| 8 |
|
Atlético San Luis | 16 | 2 | 1 | 13 | 17:62 | -45 | 7 |
| 9 |
|
Mazatlán FC | 16 | 1 | 1 | 14 | 16:53 | -37 | 4 |
| Play-off | |
| Play-off |
