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| 07.08.2021 | 16:00 | FK Spartaks | - | BFC Daugavpils | 0:1 (0:0) | |
| 17:00 | SK Spēks | - | FK Dinamo Rīga | 0:2 (0:0) | ||
| 19:00 | FK Smiltene | - | FK Liepāja | 0:3 (0:0) | ||
| 08.08.2021 | 13:00 | FK Auda | - | FK Metta | 3:1 (2:0) | |
| 15:00 | Rēzeknes FA | - | Albatroz SC | 0:3 (0:0) | ||
| 17:00 | FK Tukums 2000 | - | Riga FC | 1:3 (0:1) | ||
| 09.08.2021 | 12:30 | Skanstes SK | - | FK RFS | 0:2 (0:1) |
