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| H (Match allé) | Ñañas | - | Barcelona | 4:2 (0:1) | ||
| R (match retour) | Barcelona | - | Ñañas | 1:0 (1:0) | ||
| H (Match allé): 05.12.2020 18:00 | R (match retour): 10.12.2020 19:00 | vainqueur: Ñañas | ||||
| H (Match allé) | LDU Quito | - | El Nacional | 0:2 (0:2) | ||
| R (match retour) | El Nacional | - | LDU Quito | 3:1 (1:1) | ||
| H (Match allé): 07.12.2020 19:30 | R (match retour): 10.12.2020 21:30 | vainqueur: El Nacional | ||||
