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| 07.07.2010 | 17:30 | FK Baranovichi | - | BATE Borisov | 0:3 | |
| 17.07.2010 | 14:00 | FK Gorodeya | - | Granit Mikashevichi | 3:0 | |
| 16:00 | FK Gomelzheldortrans | - | Neman Grodno | 1:5 | ||
| 17:00 | Khimik Svetlogorsk | - | FK Vitebsk | 2:3 ap | ||
| 17:00 | Veras Nesvizh | - | Shakhter Soligorsk | 0:3 | ||
| 17:00 | FK Polotsk | - | DSK Gomel | 0:1 | ||
| 17:00 | FK Lida | - | Belshina Bobruisk | 1:3 | ||
| 17:00 | Slutsksakhar Slutsk | - | FK Minsk | 0:7 | ||
| 17:00 | FK Molodechno | - | FK Gomel | 0:5 | ||
| 17:00 | FK Osipovichi | - | Volna Pinsk | 0:7 | ||
| 18.07.2010 | 16:30 | FK Slaviya Mozyr | - | Naftan Novopolotsk | 0:1 | |
| 17:00 | FK Vedrich-97 | - | Dinamo Brest | 0:2 | ||
| 17:00 | Kommunalnik Slonim | - | Torpedo Zhodino | 2:0 | ||
| 17:00 | SKVICh Minsk | - | Partizan Minsk | 2:4 tab | ||
| 17:00 | FK Rudensk | - | Dnepr Mogilev | 2:1 | ||
| 18:00 | FK Smorgon | - | Dinamo Minsk | 1:2 |
