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| 04.02.2022 | 18:00 | Bruk-Bet Termalica Nieciecza | - | Jagiellonia Białystok | 2:1 (1:0) | |
| 20:30 | Zagłębie Lubin | - | Legia Warszawa | 1:3 (0:2) | ||
| 05.02.2022 | 15:00 | FKS Stal Mielec | - | Górnik Zabrze | 1:2 (1:0) | |
| 17:30 | Piast Gliwice | - | Pogoń Szczecin | 0:2 (0:0) | ||
| 20:00 | Lechia Gdańsk | - | Śląsk Wrocław | 2:0 (1:0) | ||
| 06.02.2022 | 12:30 | Warta Poznań | - | Górnik Łęczna | 1:1 (0:0) | |
| 15:00 | Raków Częstochowa | - | Wisła Kraków | 2:0 (0:0) | ||
| 17:30 | KS Cracovia | - | Lech Poznań | 3:3 (1:1) | ||
| 07.02.2022 | 18:00 | Radomiak Radom | - | Wisła Płock | 1:1 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Lech Poznań | 20 | 12 | 6 | 2 | 40:16 | 24 | 42 |
| 2 |
|
Pogoń Szczecin | 20 | 11 | 7 | 2 | 37:16 | 21 | 40 |
| 3 |
|
Raków Częstochowa | 20 | 11 | 5 | 4 | 38:22 | 16 | 38 |
| 4 |
|
Lechia Gdańsk | 20 | 10 | 6 | 4 | 35:23 | 12 | 36 |
| 5 |
|
Radomiak Radom | 20 | 9 | 9 | 2 | 29:17 | 12 | 36 |
| 6 |
|
Górnik Zabrze | 20 | 9 | 4 | 7 | 29:27 | 2 | 31 |
| 7 |
|
Wisła Płock | 20 | 9 | 3 | 8 | 30:27 | 3 | 30 |
| 8 |
|
FKS Stal Mielec | 20 | 7 | 7 | 6 | 27:28 | -1 | 28 |
| 9 |
|
KS Cracovia | 20 | 7 | 6 | 7 | 28:29 | -1 | 27 |
| 10 |
|
Śląsk Wrocław | 20 | 6 | 6 | 8 | 30:32 | -2 | 24 |
| 11 |
|
Jagiellonia Białystok | 20 | 6 | 6 | 8 | 25:33 | -8 | 24 |
| 12 |
|
Piast Gliwice | 20 | 6 | 5 | 9 | 26:28 | -2 | 23 |
| 13 |
|
Legia Warszawa | 20 | 7 | 0 | 13 | 26:32 | -6 | 21 |
| 14 |
|
Wisła Kraków | 20 | 6 | 3 | 11 | 21:32 | -11 | 21 |
| 15 |
|
Zagłębie Lubin | 20 | 6 | 2 | 12 | 21:39 | -18 | 20 |
| 16 |
|
Górnik Łęczna | 20 | 4 | 7 | 9 | 20:37 | -17 | 19 |
| 17 |
|
Warta Poznań | 20 | 3 | 8 | 9 | 15:25 | -10 | 17 |
| 18 |
|
Bruk-Bet Termalica Nieciecza | 20 | 3 | 6 | 11 | 23:37 | -14 | 15 |
| Champions League Quali. | |
| Relégation |
