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| 10.10.2021 | 14:00 | ADO '20 | - | RKVV Westlandia | 3:0 (1:0) | |
| 14:00 | VV Dongen | - | Blauw Geel '38 | 2:1 (0:0) | ||
| 14:00 | HVV Hollandia | - | RKSV Groene Ster | 3:0 (1:0) | ||
| 14:00 | JOS Watergraafsmeer | - | OSS '20 | 3:3 (2:2) | ||
| 14:00 | VV Gemert | - | USV Hercules | 2:2 (0:1) | ||
| 14:30 | HSC'21 | - | VV Hoogland | 4:1 (1:0) | ||
| 14:30 | EVV | - | Quick Den Haag | 1:0 (0:0) | ||
| 14:30 | OFC Oostzaan | - | RKVV DEM | 3:1 (0:1) | ||
| 14:30 | VV UNA | - | Unitas Gorinchem | 3:2 (1:1) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
OFC Oostzaan | 8 | 6 | 1 | 1 | 17:8 | 9 | 19 |
| 2 |
|
Unitas Gorinchem | 8 | 5 | 1 | 2 | 16:11 | 5 | 16 |
| 3 |
|
OSS '20 | 8 | 5 | 1 | 2 | 17:11 | 6 | 15 |
| 4 |
|
VV UNA | 8 | 5 | 0 | 3 | 17:15 | 2 | 15 |
| 5 |
|
USV Hercules | 8 | 4 | 2 | 2 | 17:11 | 6 | 14 |
| 6 |
|
VV Gemert | 8 | 3 | 5 | 0 | 15:10 | 5 | 14 |
| 7 |
|
ADO '20 | 8 | 4 | 0 | 4 | 16:13 | 3 | 12 |
| 8 |
|
RKSV Groene Ster | 8 | 3 | 2 | 3 | 13:15 | -2 | 11 |
| 9 |
|
Quick Den Haag | 8 | 3 | 1 | 4 | 7:7 | 0 | 10 |
| 10 |
|
EVV | 8 | 2 | 4 | 2 | 6:7 | -1 | 10 |
| 11 |
|
Blauw Geel '38 | 8 | 3 | 1 | 4 | 10:14 | -4 | 10 |
| 12 |
|
JOS Watergraafsmeer | 8 | 3 | 2 | 3 | 14:13 | 1 | 9 |
| 13 |
|
RKVV Westlandia | 8 | 2 | 3 | 3 | 12:11 | 1 | 9 |
| 14 |
|
VV Dongen | 8 | 2 | 3 | 3 | 11:11 | 0 | 9 |
| 15 |
|
HVV Hollandia | 8 | 2 | 3 | 3 | 8:9 | -1 | 9 |
| 16 |
|
VV Hoogland | 8 | 1 | 3 | 4 | 7:18 | -11 | 6 |
| 17 |
|
HSC'21 | 8 | 1 | 2 | 5 | 10:16 | -6 | 5 |
| 18 |
|
RKVV DEM | 8 | 0 | 2 | 6 | 3:16 | -13 | 2 |
| Promotion | |
| Relégation | |
| Relégation |
