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| 23.10.2021 | 15:00 | Sportlust '46 | - | AFC Ajax Zaterdag | 9:0 (4:0) | |
| 30.10.2021 | 14:30 | VV Staphorst | - | HSV Hoek | 1:0 (0:0) | |
| 14:30 | Excelsior '31 | - | FC Lisse | 1:3 (1:0) | ||
| 14:30 | VV GOES | - | VVOG Harderwijk | 2:2 (1:1) | ||
| 14:30 | BVV Barendrecht | - | ODIN '59 | 5:0 (2:0) | ||
| 14:30 | DVS'33 | - | Sparta Nijkerk | 2:1 (1:0) | ||
| 14:30 | SteDoCo | - | ACV Assen | 2:1 (1:0) | ||
| 15:00 | Ter Leede | - | Harkemase Boys | 0:1 (0:1) | ||
| 18:00 | VV Sint Bavo | - | VV DOVO Veenendaal | 0:3 (0:1) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sportlust '46 | 10 | 6 | 2 | 2 | 23:13 | 10 | 20 |
| 2 |
|
FC Lisse | 10 | 6 | 2 | 2 | 20:10 | 10 | 20 |
| 3 |
|
Sparta Nijkerk | 10 | 6 | 2 | 2 | 18:9 | 9 | 20 |
| 4 |
|
Harkemase Boys | 10 | 5 | 3 | 2 | 21:17 | 4 | 18 |
| 5 |
|
DVS'33 | 10 | 5 | 2 | 3 | 17:9 | 8 | 17 |
| 6 |
|
Excelsior '31 | 10 | 5 | 2 | 3 | 20:13 | 7 | 17 |
| 7 |
|
VV Staphorst | 10 | 4 | 4 | 2 | 14:7 | 7 | 16 |
| 8 |
|
ACV Assen | 10 | 4 | 2 | 4 | 17:14 | 3 | 14 |
| 9 |
|
SteDoCo | 10 | 4 | 2 | 4 | 14:12 | 2 | 14 |
| 10 |
|
BVV Barendrecht | 10 | 3 | 4 | 3 | 19:16 | 3 | 13 |
| 11 |
|
Ter Leede | 10 | 4 | 1 | 5 | 11:18 | -7 | 13 |
| 12 |
|
HSV Hoek | 10 | 3 | 3 | 4 | 16:17 | -1 | 12 |
| 13 |
|
VVOG Harderwijk | 10 | 2 | 4 | 4 | 15:25 | -10 | 10 |
| 14 |
|
AFC Ajax Zaterdag | 10 | 3 | 1 | 6 | 9:20 | -11 | 10 |
| 15 |
|
VV DOVO Veenendaal | 10 | 2 | 3 | 5 | 10:17 | -7 | 9 |
| 16 |
|
VV Sint Bavo | 10 | 2 | 3 | 5 | 11:19 | -8 | 9 |
| 17 |
|
ODIN '59 | 10 | 2 | 2 | 6 | 10:21 | -11 | 8 |
| 18 |
|
VV GOES | 10 | 0 | 6 | 4 | 13:21 | -8 | 6 |
| Promotion | |
| Relégation | |
| Relégation |
