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| 06.03.2022 | 14:30 | US Breno | - | Olginatese | 1:0 | |
| 14:30 | Castellanzese | - | AC Pontisola | 2:3 | ||
| 14:30 | US Ciserano | - | Sona | 3:1 | ||
| 14:30 | AC Crema | - | USD Casatese | 0:0 | ||
| 14:30 | Franciacorta | - | USD Caravaggio | 2:0 | ||
| 14:30 | Legnano | - | AC Calvina Sport | 2:2 | ||
| 14:30 | AC Leon | - | Vis Nova Giussano | 2:2 | ||
| 14:30 | Real Calepina | - | GS Arconatese 1926 | 1:0 | ||
| 14:30 | SG City Nova | - | Brusaporto | 1:2 | ||
| 14:30 | Villa d'Almè | - | US Folgore Caratese | 1:3 |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SG City Nova | 27 | 17 | 5 | 5 | 54:31 | 23 | 56 |
| 2 |
|
Brusaporto | 27 | 14 | 8 | 5 | 46:32 | 14 | 50 |
| 3 |
|
US Folgore Caratese | 27 | 14 | 7 | 6 | 47:35 | 12 | 49 |
| 4 |
|
Legnano | 27 | 14 | 5 | 8 | 37:33 | 4 | 47 |
| 5 |
|
AC Calvina Sport | 27 | 13 | 8 | 6 | 45:32 | 13 | 47 |
| 6 |
|
USD Casatese | 27 | 11 | 10 | 6 | 47:31 | 16 | 43 |
| 7 |
|
GS Arconatese 1926 | 27 | 11 | 9 | 7 | 44:34 | 10 | 42 |
| 8 |
|
US Breno | 27 | 11 | 8 | 8 | 42:32 | 10 | 41 |
| 9 |
|
US Ciserano | 27 | 10 | 10 | 7 | 44:38 | 6 | 40 |
| 10 |
|
Franciacorta | 27 | 9 | 10 | 8 | 49:55 | -6 | 37 |
| 11 |
|
AC Crema | 27 | 10 | 7 | 10 | 30:30 | 0 | 37 |
| 12 |
|
AC Pontisola | 27 | 8 | 9 | 10 | 43:43 | 0 | 33 |
| 13 |
|
Castellanzese | 27 | 9 | 4 | 14 | 34:41 | -7 | 31 |
| 14 |
|
Real Calepina | 27 | 7 | 9 | 11 | 25:26 | -1 | 30 |
| 15 |
|
Sona | 27 | 7 | 8 | 12 | 32:44 | -12 | 29 |
| 16 |
|
Vis Nova Giussano | 27 | 8 | 3 | 16 | 45:55 | -10 | 27 |
| 17 |
|
USD Caravaggio | 27 | 5 | 10 | 12 | 31:46 | -15 | 25 |
| 18 |
|
Olginatese | 27 | 5 | 9 | 13 | 26:39 | -13 | 24 |
| 19 |
|
Villa d'Almè | 27 | 4 | 10 | 13 | 29:46 | -17 | 22 |
| 20 |
|
AC Leon | 27 | 5 | 7 | 15 | 33:60 | -27 | 22 |
| Promotion | |
| Play-off | |
| Relégation | |
| Relégation |
