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| 27.02.2022 | 14:30 | GS Arconatese 1926 | - | Villa d'Almè | 2:3 | |
| 14:30 | Brusaporto | - | US Breno | 1:0 | ||
| 14:30 | AC Calvina Sport | - | Castellanzese | 0:1 | ||
| 14:30 | US Folgore Caratese | - | AC Leon | 1:0 | ||
| 14:30 | AC Pontisola | - | SG City Nova | 2:3 | ||
| 14:30 | Sona | - | Franciacorta | 1:1 | ||
| 14:30 | USD Caravaggio | - | Real Calepina | 0:1 | ||
| 14:30 | USD Casatese | - | Legnano | 2:0 | ||
| 14:30 | Olginatese | - | AC Crema | 0:1 | ||
| 14:30 | Vis Nova Giussano | - | US Ciserano | 3:1 |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SG City Nova | 26 | 17 | 5 | 4 | 53:29 | 24 | 56 |
| 2 |
|
Brusaporto | 26 | 13 | 8 | 5 | 44:31 | 13 | 47 |
| 3 |
|
Legnano | 26 | 14 | 4 | 8 | 35:31 | 4 | 46 |
| 4 |
|
US Folgore Caratese | 26 | 13 | 7 | 6 | 44:34 | 10 | 46 |
| 5 |
|
AC Calvina Sport | 26 | 13 | 7 | 6 | 43:30 | 13 | 46 |
| 6 |
|
USD Casatese | 26 | 11 | 9 | 6 | 47:31 | 16 | 42 |
| 7 |
|
GS Arconatese 1926 | 26 | 11 | 9 | 6 | 44:33 | 11 | 42 |
| 8 |
|
US Breno | 26 | 10 | 8 | 8 | 41:32 | 9 | 38 |
| 9 |
|
US Ciserano | 26 | 9 | 10 | 7 | 41:37 | 4 | 37 |
| 10 |
|
AC Crema | 26 | 10 | 6 | 10 | 30:30 | 0 | 36 |
| 11 |
|
Franciacorta | 26 | 8 | 10 | 8 | 47:55 | -8 | 34 |
| 12 |
|
Castellanzese | 26 | 9 | 4 | 13 | 32:38 | -6 | 31 |
| 13 |
|
AC Pontisola | 26 | 7 | 9 | 10 | 40:41 | -1 | 30 |
| 14 |
|
Sona | 26 | 7 | 8 | 11 | 31:41 | -10 | 29 |
| 15 |
|
Real Calepina | 26 | 6 | 9 | 11 | 24:26 | -2 | 27 |
| 16 |
|
Vis Nova Giussano | 26 | 8 | 2 | 16 | 43:53 | -10 | 26 |
| 17 |
|
USD Caravaggio | 26 | 5 | 10 | 11 | 31:44 | -13 | 25 |
| 18 |
|
Olginatese | 26 | 5 | 9 | 12 | 26:38 | -12 | 24 |
| 19 |
|
Villa d'Almè | 26 | 4 | 10 | 12 | 28:43 | -15 | 22 |
| 20 |
|
AC Leon | 26 | 5 | 6 | 15 | 31:58 | -27 | 21 |
| Promotion | |
| Play-off | |
| Relégation | |
| Relégation |
