 |
 |
|
|
| 16.10.2021 | 17:15 | Apollon Smyrnis | - | Asteras Tripolis | 0:1 (0:0) | |
| 19:30 | Panathinaikos | - | Ionikos Nikea | 4:1 (2:1) | ||
| 17.10.2021 | 15:00 | Panetolikos | - | OFI Heraklion | 1:2 (1:1) | |
| 15:00 | PAOK Saloniki | - | Volos NFC | 4:4 (4:1) | ||
| 19:30 | AEK Athen | - | Atromitos | 3:0 (1:0) | ||
| 19:30 | PAS Giannina | - | Olympiakos Piraeus | 1:2 (0:1) | ||
| 18.10.2021 | 18:30 | Lamia | - | Aris Saloniki | 0:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Olympiakos Piraeus | 6 | 4 | 2 | 0 | 10:3 | 7 | 14 |
| 2 |
|
AEK Athen | 6 | 4 | 1 | 1 | 13:6 | 7 | 13 |
| 3 |
|
PAOK Saloniki | 6 | 4 | 1 | 1 | 12:7 | 5 | 13 |
| 4 |
|
Volos NFC | 6 | 4 | 1 | 1 | 15:12 | 3 | 13 |
| 5 |
|
Aris Saloniki | 6 | 3 | 2 | 1 | 5:2 | 3 | 11 |
| 6 |
|
Panathinaikos | 6 | 3 | 1 | 2 | 13:4 | 9 | 10 |
| 7 |
|
PAS Giannina | 6 | 2 | 3 | 1 | 5:4 | 1 | 9 |
| 8 |
|
OFI Heraklion | 6 | 1 | 4 | 1 | 7:8 | -1 | 7 |
| 9 |
|
Panetolikos | 6 | 1 | 2 | 3 | 7:10 | -3 | 5 |
| 10 |
|
Ionikos Nikea | 6 | 1 | 2 | 3 | 3:9 | -6 | 5 |
| 11 |
|
Asteras Tripolis | 6 | 1 | 2 | 3 | 2:5 | -3 | 5 |
| 12 |
|
Lamia | 6 | 1 | 1 | 4 | 6:9 | -3 | 4 |
| 13 |
|
Atromitos | 6 | 0 | 2 | 4 | 3:12 | -9 | 2 |
| 14 |
|
Apollon Smyrnis | 6 | 0 | 2 | 4 | 2:12 | -10 | 2 |
| Play-off | |
| Relégation |
