 |
 |
|
|
| 20.11.2021 | 14:00 | Volos NFC | - | OFI Heraklion | 0:2 (0:1) | |
| 18:30 | Aris Saloniki | - | PAS Giannina | 0:5 (0:2) | ||
| 18:30 | Ionikos Nikea | - | Asteras Tripolis | 1:1 (1:1) | ||
| 21.11.2021 | 16:15 | Panetolikos | - | Apollon Smyrnis | 1:0 (0:0) | |
| 18:30 | AEK Athen | - | Olympiakos Piraeus | 2:3 (1:2) | ||
| 18:30 | Atromitos | - | PAOK Saloniki | 2:0 (1:0) | ||
| 22.11.2021 | 17:00 | Lamia | - | Panathinaikos | 1:3 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Olympiakos Piraeus | 10 | 8 | 2 | 0 | 18:7 | 11 | 26 |
| 2 |
|
AEK Athen | 10 | 6 | 2 | 2 | 22:13 | 9 | 20 |
| 3 |
|
PAOK Saloniki | 10 | 6 | 1 | 3 | 20:13 | 7 | 19 |
| 4 |
|
Aris Saloniki | 10 | 5 | 2 | 3 | 13:11 | 2 | 17 |
| 5 |
|
PAS Giannina | 10 | 4 | 4 | 2 | 14:6 | 8 | 16 |
| 6 |
|
OFI Heraklion | 10 | 3 | 6 | 1 | 11:8 | 3 | 15 |
| 7 |
|
Panathinaikos | 10 | 4 | 2 | 4 | 18:10 | 8 | 14 |
| 8 |
|
Volos NFC | 10 | 4 | 2 | 4 | 18:20 | -2 | 14 |
| 9 |
|
Ionikos Nikea | 10 | 2 | 4 | 4 | 7:12 | -5 | 10 |
| 10 |
|
Asteras Tripolis | 10 | 2 | 4 | 4 | 6:9 | -3 | 10 |
| 11 |
|
Lamia | 10 | 2 | 3 | 5 | 10:14 | -4 | 9 |
| 12 |
|
Panetolikos | 10 | 2 | 2 | 6 | 10:20 | -10 | 8 |
| 13 |
|
Atromitos | 10 | 1 | 3 | 6 | 7:18 | -11 | 6 |
| 14 |
|
Apollon Smyrnis | 10 | 1 | 3 | 6 | 6:19 | -13 | 6 |
| Play-off | |
| Relégation |
