 |
 |
| 02.02.2021 | 13:00 | Dinamo Moskva | - | FK Rudar Pljevlja | 3:1 (0:0) | |
| 13:00 | Rubin Kazan | - | FK Khimki | 2:2 (2:0) | ||
| 14:00 | NAC Breda | - | FC Utrecht | 2:2 (1:2) | ||
| 14:30 | Levski Sofia | - | FK Sarajevo | 0:1 (0:0) | ||
| 03.02.2021 | 15:00 | Shakhtar Donetsk | - | Slovan Bratislava | 0:1 (0:0) | |
| 04.02.2021 | 11:00 | Dinamo Moskva | - | FK Kairat | 2:0 (1:0) | |
| 14:00 | FC Liefering | - | Grazer AK | 1:0 (0:0) | ||
| 14:00 | Lokomotiv Moskva | - | FK Krasnodar | 1:1 (0:1) | ||
| 05.02.2021 | Molde FK | - | FK Bodø/Glimt | pas disputer | ||
| 12:30 | Rubin Kazan | - | Dinamo Moskva | 2:3 (1:2) | ||
| 14:00 | FC Liefering | - | Floridsdorfer AC | 1:1 (1:1) | ||
| 15:00 | SKN St. Pölten | - | FC Wacker Innsbruck | 2:1 (1:0) | ||
| 15:00 | TSV Hartberg | - | SV Lafnitz | 2:1 | ||
| 15:00 | Vorwärts Steyr | - | FC Blau Weiß Linz | 3:1 | ||
| 06.02.2021 | 13:00 | Spartak Moskva | - | Shakhter Soligorsk | 2:1 (0:1) | |
| 07.02.2021 | 13:00 | Spartak Moskva | - | Riga FC | 4:0 |
