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| 05.02.2023 | 12:00 | Cádiz CF B | - | FC Cartagena B | 1:1 (1:0) | |
| 12:00 | Atlético Mancha Real | - | Juventud Torremolinos | 0:4 (0:1) | ||
| 12:00 | UCAM Murcia CF | - | Vélez CF | 4:0 (1:0) | ||
| 12:30 | Atlético Sanluqueño CF | - | Mar Menor CF | 1:1 (0:1) | ||
| 13:00 | Real Betis B | - | Recreativo Huelva | 0:0 (0:0) | ||
| 16:15 | CD San Roque | - | Sevilla Atlético | 1:0 (1:0) | ||
| 17:00 | Antequera CF | - | Recreativo Granada | 1:1 (1:1) | ||
| 17:00 | CD El Ejido 2012 | - | Utrera CD | 5:0 (2:0) | ||
| 17:00 | Yeclano Deportivo | - | Xerez DFC | 1:0 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Antequera CF | 20 | 15 | 4 | 1 | 40:14 | 26 | 49 |
| 2 |
|
Recreativo Huelva | 20 | 10 | 7 | 3 | 25:16 | 9 | 37 |
| 3 |
|
UCAM Murcia CF | 20 | 8 | 7 | 5 | 30:20 | 10 | 31 |
| 4 |
|
Atlético Sanluqueño CF | 20 | 8 | 7 | 5 | 26:21 | 5 | 31 |
| 5 |
|
Yeclano Deportivo | 20 | 8 | 7 | 5 | 20:16 | 4 | 31 |
| 6 |
|
Vélez CF | 20 | 9 | 3 | 8 | 21:25 | -4 | 30 |
| 7 |
|
Recreativo Granada | 20 | 8 | 5 | 7 | 26:21 | 5 | 29 |
| 8 |
|
Mar Menor CF | 20 | 7 | 8 | 5 | 21:18 | 3 | 29 |
| 9 |
|
FC Cartagena B | 20 | 8 | 4 | 8 | 21:25 | -4 | 28 |
| 10 |
|
CD San Roque | 20 | 7 | 5 | 8 | 22:20 | 2 | 26 |
| 11 |
|
Real Betis B | 20 | 6 | 7 | 7 | 16:19 | -3 | 25 |
| 12 |
|
Atlético Mancha Real | 20 | 7 | 4 | 9 | 15:26 | -11 | 25 |
| 13 |
|
Juventud Torremolinos | 20 | 5 | 8 | 7 | 19:20 | -1 | 23 |
| 14 |
|
CD El Ejido 2012 | 20 | 6 | 4 | 10 | 20:22 | -2 | 22 |
| 15 |
|
Cádiz CF B | 20 | 5 | 7 | 8 | 22:27 | -5 | 22 |
| 16 |
|
Xerez DFC | 20 | 5 | 6 | 9 | 16:21 | -5 | 21 |
| 17 |
|
Sevilla Atlético | 20 | 5 | 2 | 13 | 19:25 | -6 | 17 |
| 18 |
|
Utrera CD | 20 | 4 | 3 | 13 | 16:39 | -23 | 15 |
| Promotion | |
| Play-off | |
| Relégation |
