 |
 |
|
| 15.10.2021 | 19:00 | CE Sabadell | - | Atlético Sanluqueño CF | 1:0 (0:0) | |
| 21:00 | FC Andorra | - | San Fernando CD | 1:0 (1:0) | ||
| 21:00 | CD Alcoyano | - | UCAM Murcia CF | 3:2 (0:0) | ||
| 16.10.2021 | 17:00 | CD Castellón | - | Gimnàstic de Tarragona | 1:1 (1:0) | |
| 17:00 | Linares Deportivo | - | Algeciras CF | 0:3 (0:3) | ||
| 19:00 | Real Betis B | - | Villarreal CF B | 1:2 (1:0) | ||
| 21:00 | Real Madrid Castilla | - | FC Barcelona B | 0:0 (0:0) | ||
| 17.10.2021 | 12:00 | UE Costa Brava | - | Atlético Baleares | 1:2 (1:0) | |
| 12:00 | RB Linense | - | UE Cornellà | 1:0 (1:0) | ||
| 17:00 | Sevilla Atlético | - | Albacete | 0:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Villarreal CF B | 8 | 7 | 1 | 0 | 19:3 | 16 | 22 |
| 2 |
|
Atlético Baleares | 8 | 4 | 4 | 0 | 14:7 | 7 | 16 |
| 3 |
|
Albacete | 8 | 5 | 1 | 2 | 12:9 | 3 | 16 |
| 4 |
|
Algeciras CF | 8 | 4 | 3 | 1 | 18:9 | 9 | 15 |
| 5 |
|
Gimnàstic de Tarragona | 8 | 4 | 2 | 2 | 8:6 | 2 | 14 |
| 6 |
|
RB Linense | 8 | 4 | 2 | 2 | 8:8 | 0 | 14 |
| 7 |
|
FC Andorra | 8 | 3 | 3 | 2 | 10:8 | 2 | 12 |
| 8 |
|
Atlético Sanluqueño CF | 8 | 3 | 3 | 2 | 7:5 | 2 | 12 |
| 9 |
|
CD Alcoyano | 8 | 3 | 3 | 2 | 12:11 | 1 | 12 |
| 10 |
|
FC Barcelona B | 8 | 3 | 3 | 2 | 8:7 | 1 | 12 |
| 11 |
|
CD Castellón | 8 | 3 | 2 | 3 | 8:7 | 1 | 11 |
| 12 |
|
UE Cornellà | 8 | 3 | 1 | 4 | 9:8 | 1 | 10 |
| 13 |
|
UCAM Murcia CF | 8 | 2 | 2 | 4 | 9:10 | -1 | 8 |
| 14 |
|
Real Madrid Castilla | 8 | 2 | 2 | 4 | 9:11 | -2 | 8 |
| 15 |
|
San Fernando CD | 8 | 2 | 2 | 4 | 9:14 | -5 | 8 |
| 16 |
|
CE Sabadell | 8 | 1 | 4 | 3 | 3:6 | -3 | 7 |
| 17 |
|
Linares Deportivo | 8 | 1 | 3 | 4 | 7:13 | -6 | 6 |
| 18 |
|
UE Costa Brava | 8 | 1 | 3 | 4 | 4:13 | -9 | 6 |
| 19 |
|
Real Betis B | 8 | 1 | 1 | 6 | 3:11 | -8 | 4 |
| 20 |
|
Sevilla Atlético | 8 | 1 | 1 | 6 | 6:17 | -11 | 4 |
| Promotion | |
| Play-off | |
| Relégation |
