 |
 |
|
| 13.11.2021 | 17:00 | Linares Deportivo | - | Villarreal CF B | 2:1 (0:1) | |
| 19:00 | Atlético Sanluqueño CF | - | FC Barcelona B | 0:2 (0:1) | ||
| 21:00 | CD Alcoyano | - | Atlético Baleares | 0:0 (0:0) | ||
| 21:00 | Real Betis B | - | UE Cornellà | 1:3 (1:1) | ||
| 21:00 | RB Linense | - | Albacete | 4:1 (1:1) | ||
| 14.11.2021 | 12:00 | Real Madrid Castilla | - | Algeciras CF | 2:0 (1:0) | |
| 12:00 | Sevilla Atlético | - | FC Andorra | 1:1 (1:1) | ||
| 17:00 | CE Sabadell | - | San Fernando CD | 2:3 (2:0) | ||
| 17:00 | Gimnàstic de Tarragona | - | UCAM Murcia CF | 2:2 (1:2) | ||
| 08.12.2021 | 17:00 | CD Castellón | - | UE Costa Brava | 1:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Villarreal CF B | 12 | 8 | 1 | 3 | 23:8 | 15 | 25 |
| 2 |
|
Atlético Baleares | 12 | 6 | 5 | 1 | 19:10 | 9 | 23 |
| 3 |
|
FC Barcelona B | 12 | 6 | 4 | 2 | 16:8 | 8 | 22 |
| 4 |
|
Albacete | 12 | 7 | 1 | 4 | 15:14 | 1 | 22 |
| 5 |
|
CD Castellón | 12 | 6 | 3 | 3 | 13:9 | 4 | 21 |
| 6 |
|
RB Linense | 12 | 6 | 3 | 3 | 13:10 | 3 | 21 |
| 7 |
|
FC Andorra | 12 | 5 | 4 | 3 | 15:12 | 3 | 19 |
| 8 |
|
Gimnàstic de Tarragona | 12 | 5 | 4 | 3 | 13:11 | 2 | 19 |
| 9 |
|
Algeciras CF | 12 | 4 | 6 | 2 | 19:12 | 7 | 18 |
| 10 |
|
CD Alcoyano | 12 | 4 | 6 | 2 | 13:11 | 2 | 18 |
| 11 |
|
Atlético Sanluqueño CF | 12 | 5 | 3 | 4 | 12:10 | 2 | 18 |
| 12 |
|
Real Madrid Castilla | 12 | 5 | 2 | 5 | 15:15 | 0 | 17 |
| 13 |
|
UE Cornellà | 12 | 5 | 1 | 6 | 14:12 | 2 | 16 |
| 14 |
|
San Fernando CD | 12 | 4 | 2 | 6 | 15:19 | -4 | 14 |
| 15 |
|
UCAM Murcia CF | 12 | 3 | 4 | 5 | 15:16 | -1 | 13 |
| 16 |
|
CE Sabadell | 12 | 2 | 5 | 5 | 8:13 | -5 | 11 |
| 17 |
|
Linares Deportivo | 12 | 2 | 3 | 7 | 11:20 | -9 | 9 |
| 18 |
|
Real Betis B | 12 | 2 | 2 | 8 | 7:17 | -10 | 8 |
| 19 |
|
UE Costa Brava | 12 | 1 | 4 | 7 | 4:17 | -13 | 7 |
| 20 |
|
Sevilla Atlético | 12 | 1 | 3 | 8 | 8:24 | -16 | 6 |
| Promotion | |
| Play-off | |
| Relégation |
