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| 21.02.2009 | 20:00 | FC Barcelona | - | Espanyol Barcelona | 1:2 (0:0) | |
| 20:00 | Real Madrid | - | Real Betis | 6:1 (6:1) | ||
| 20:00 | Villarreal CF | - | Sporting Gijón | 2:1 (2:1) | ||
| 22:00 | Sevilla FC | - | Atlético Madrid | 1:0 (0:0) | ||
| 22.02.2009 | 17:00 | Real Valladolid | - | Málaga CF | 1:3 (0:2) | |
| 17:00 | Recreativo Huelva | - | UD Almería | 1:1 (0:0) | ||
| 17:00 | RCD Mallorca | - | Racing Santander | 1:0 (0:0) | ||
| 17:00 | CA Osasuna | - | CD Numancia | 2:0 (2:0) | ||
| 19:00 | Getafe CF | - | Athletic Bilbao | 1:1 (1:1) | ||
| 21:00 | Deportivo La Coruña | - | Valencia CF | 1:1 (0:1) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Barcelona | 24 | 19 | 3 | 2 | 71:20 | 51 | 60 |
| 2 |
|
Real Madrid | 24 | 17 | 2 | 5 | 55:28 | 27 | 53 |
| 3 |
|
Sevilla FC | 24 | 13 | 5 | 6 | 32:21 | 11 | 44 |
| 4 |
|
Villarreal CF | 24 | 11 | 8 | 5 | 38:32 | 6 | 41 |
| 5 |
|
Valencia CF | 24 | 11 | 6 | 7 | 44:35 | 9 | 39 |
| 6 |
|
Málaga CF | 24 | 11 | 6 | 7 | 41:35 | 6 | 39 |
| 7 |
|
Atlético Madrid | 24 | 10 | 6 | 8 | 48:35 | 13 | 36 |
| 8 |
|
Deportivo La Coruña | 24 | 10 | 6 | 8 | 28:30 | -2 | 36 |
| 9 |
|
Athletic Bilbao | 24 | 8 | 7 | 9 | 34:37 | -3 | 31 |
| 10 |
|
Real Valladolid | 24 | 9 | 3 | 12 | 35:39 | -4 | 30 |
| 11 |
|
Racing Santander | 24 | 7 | 8 | 9 | 25:28 | -3 | 29 |
| 12 |
|
Getafe CF | 24 | 6 | 10 | 8 | 34:36 | -2 | 28 |
| 13 |
|
UD Almería | 24 | 7 | 7 | 10 | 30:38 | -8 | 28 |
| 14 |
|
Sporting Gijón | 24 | 9 | 0 | 15 | 30:53 | -23 | 27 |
| 15 |
|
Real Betis | 24 | 7 | 5 | 12 | 32:38 | -6 | 26 |
| 16 |
|
Recreativo Huelva | 24 | 6 | 8 | 10 | 21:34 | -13 | 26 |
| 17 |
|
CA Osasuna | 24 | 5 | 9 | 10 | 25:30 | -5 | 24 |
| 18 |
|
RCD Mallorca | 24 | 6 | 6 | 12 | 24:40 | -16 | 24 |
| 19 |
|
Espanyol Barcelona | 24 | 4 | 9 | 11 | 22:38 | -16 | 21 |
| 20 |
|
CD Numancia | 24 | 6 | 2 | 16 | 26:48 | -22 | 20 |
| Champions League | |
| Champions League Quali. | |
| Europa League | |
| Relégation |
