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| 30.01.2021 | 14:00 | FK Teplice | - | MFK Karviná | 2:2 (2:0) | |
| 16:00 | 1. FC Slovácko | - | Dynamo České Budějovice | 0:0 (0:0) | ||
| 16:00 | FK Pardubice | - | 1. FK Příbram | 1:0 (0:0) | ||
| 18:30 | AC Sparta Praha | - | Bohemians Praha 1905 | 0:1 (0:1) | ||
| 31.01.2021 | 14:00 | SFC Opava | - | Zbrojovka Brno | 0:2 (0:1) | |
| 16:00 | Baník Ostrava | - | Viktoria Plzeň | 0:2 (0:0) | ||
| 18:30 | Slavia Praha | - | FK Jablonec | 3:0 (2:0) | ||
| 02.02.2021 | 15:00 | FK Mladá Boleslav | - | Sigma Olomouc | 1:1 (1:0) | |
| 17.02.2021 | 14:00 | Slovan Liberec | - | FC Fastav Zlín | 1:0 (0:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slavia Praha | 17 | 15 | 2 | 0 | 51:8 | 43 | 47 |
| 2 |
|
AC Sparta Praha | 17 | 11 | 2 | 4 | 33:19 | 14 | 35 |
|
FK Jablonec | 17 | 11 | 2 | 4 | 33:19 | 14 | 35 | |
| 4 |
|
1. FC Slovácko | 17 | 9 | 4 | 4 | 30:17 | 13 | 31 |
| 5 |
|
Slovan Liberec | 17 | 8 | 4 | 5 | 25:17 | 8 | 28 |
| 6 |
|
Viktoria Plzeň | 17 | 8 | 3 | 6 | 32:21 | 11 | 27 |
| 7 |
|
Sigma Olomouc | 17 | 6 | 8 | 3 | 26:20 | 6 | 26 |
| 8 |
|
Baník Ostrava | 17 | 7 | 5 | 5 | 21:15 | 6 | 26 |
| 9 |
|
Dynamo České Budějovice | 17 | 6 | 7 | 4 | 23:23 | 0 | 25 |
| 10 |
|
FK Pardubice | 17 | 7 | 4 | 6 | 16:19 | -3 | 25 |
| 11 |
|
MFK Karviná | 17 | 5 | 6 | 6 | 17:25 | -8 | 21 |
| 12 |
|
Bohemians Praha 1905 | 17 | 5 | 4 | 8 | 19:22 | -3 | 19 |
| 13 |
|
FC Fastav Zlín | 17 | 5 | 3 | 9 | 18:25 | -7 | 18 |
| 14 |
|
FK Teplice | 17 | 5 | 2 | 10 | 18:37 | -19 | 17 |
| 15 |
|
Zbrojovka Brno | 17 | 3 | 4 | 10 | 15:31 | -16 | 13 |
| 16 |
|
FK Mladá Boleslav | 17 | 2 | 5 | 10 | 18:31 | -13 | 11 |
| 17 |
|
1. FK Příbram | 17 | 2 | 4 | 11 | 12:33 | -21 | 10 |
| 18 |
|
SFC Opava | 17 | 1 | 5 | 11 | 11:36 | -25 | 8 |
| Champions League Quali. | |
| Europa League Quali. | |
| Relégation |
