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| H (Match allé) | Internacional | - | São Paulo FC | 2:0 (1:0) | ||
| R (match retour) | São Paulo FC | - | Internacional | 1:1 (1:1) | ||
| H (Match allé): 21.11.2021 20:00 | R (match retour): 28.11.2021 15:00 | vainqueur: Internacional | ||||
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|
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| H (Match allé) | Internacional | - | São Paulo FC | 2:0 (1:0) | ||
| R (match retour) | São Paulo FC | - | Internacional | 1:1 (1:1) | ||
| H (Match allé): 21.11.2021 20:00 | R (match retour): 28.11.2021 15:00 | vainqueur: Internacional | ||||
