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| 12.11.2022 | 11:00 | Chemnitzer FC | - | Dynamo Dresden | 3:2 (2:0) | |
| 11:00 | Erzgebirge Aue | - | Niendorfer TSV | 2:3 (0:1) | ||
| 11:00 | SV Meppen | - | VfL Wolfsburg | 0:4 (0:2) | ||
| 11:00 | Hamburger SV | - | RB Leipzig | 2:2 (1:2) | ||
| 11:00 | 1. FC Union Berlin | - | Werder Bremen | 1:5 (0:3) | ||
| 12:00 | FC Carl Zeiss Jena | - | 1. FC Magdeburg | 0:4 (0:1) | ||
| 12:00 | FC St. Pauli | - | FC Viktoria 1889 Berlin | 3:0 (1:0) | ||
| 14:00 | Hertha BSC | - | Hansa Rostock | 5:1 (4:1) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VfL Wolfsburg | 11 | 10 | 0 | 1 | 28:10 | 18 | 30 |
| 2 |
|
Hamburger SV | 10 | 6 | 3 | 1 | 27:12 | 15 | 21 |
| 3 |
|
FC St. Pauli | 11 | 6 | 3 | 2 | 20:14 | 6 | 21 |
| 4 |
|
Chemnitzer FC | 11 | 6 | 2 | 3 | 18:16 | 2 | 20 |
| 5 |
|
RB Leipzig | 10 | 6 | 1 | 3 | 25:16 | 9 | 19 |
| 6 |
|
Hertha BSC | 11 | 5 | 2 | 4 | 32:19 | 13 | 17 |
| 7 |
|
Werder Bremen | 10 | 5 | 2 | 3 | 27:24 | 3 | 17 |
| 8 |
|
1. FC Magdeburg | 11 | 5 | 2 | 4 | 20:18 | 2 | 17 |
| 9 |
|
Hannover 96 | 10 | 5 | 1 | 4 | 19:17 | 2 | 16 |
| 10 |
|
Dynamo Dresden | 10 | 4 | 2 | 4 | 23:14 | 9 | 14 |
| 11 |
|
FC Viktoria 1889 Berlin | 10 | 4 | 1 | 5 | 20:21 | -1 | 13 |
| 12 |
|
1. FC Union Berlin | 10 | 4 | 1 | 5 | 19:20 | -1 | 13 |
| 13 |
|
Niendorfer TSV | 11 | 3 | 4 | 4 | 18:26 | -8 | 13 |
| 14 |
|
SV Meppen | 10 | 1 | 3 | 6 | 12:26 | -14 | 6 |
| 15 |
|
Erzgebirge Aue | 10 | 1 | 2 | 7 | 8:19 | -11 | 5 |
| 16 |
|
Hansa Rostock | 10 | 1 | 2 | 7 | 7:24 | -17 | 5 |
| 17 |
|
FC Carl Zeiss Jena | 10 | 0 | 1 | 9 | 7:34 | -27 | 1 |
| Play-off | |
| Relégation |
