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| 05.11.2022 | 11:00 | Dynamo Dresden | - | Hannover 96 | 2:3 (0:1) | |
| 12:00 | Hansa Rostock | - | Chemnitzer FC | 1:1 (0:1) | ||
| 13:00 | VfL Wolfsburg | - | Hamburger SV | 3:2 (1:2) | ||
| 13:30 | RB Leipzig | - | 1. FC Union Berlin | 1:2 (0:1) | ||
| 14:00 | Niendorfer TSV | - | SV Meppen | 1:1 (1:1) | ||
| 14:00 | FC Viktoria 1889 Berlin | - | Hertha BSC | 2:4 (1:1) | ||
| 14:30 | 1. FC Magdeburg | - | Erzgebirge Aue | 1:0 (0:0) | ||
| 14:30 | Werder Bremen | - | FC St. Pauli | 1:1 (1:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VfL Wolfsburg | 10 | 9 | 0 | 1 | 24:10 | 14 | 27 |
| 2 |
|
Hamburger SV | 9 | 6 | 2 | 1 | 25:10 | 15 | 20 |
| 3 |
|
RB Leipzig | 9 | 6 | 0 | 3 | 23:14 | 9 | 18 |
| 4 |
|
FC St. Pauli | 10 | 5 | 3 | 2 | 17:14 | 3 | 18 |
| 5 |
|
Chemnitzer FC | 10 | 5 | 2 | 3 | 15:14 | 1 | 17 |
| 6 |
|
Hannover 96 | 10 | 5 | 1 | 4 | 19:17 | 2 | 16 |
| 7 |
|
Dynamo Dresden | 9 | 4 | 2 | 3 | 21:11 | 10 | 14 |
| 8 |
|
Hertha BSC | 10 | 4 | 2 | 4 | 27:18 | 9 | 14 |
| 9 |
|
Werder Bremen | 9 | 4 | 2 | 3 | 22:23 | -1 | 14 |
| 10 |
|
1. FC Magdeburg | 10 | 4 | 2 | 4 | 16:18 | -2 | 14 |
| 11 |
|
1. FC Union Berlin | 9 | 4 | 1 | 4 | 18:15 | 3 | 13 |
| 12 |
|
FC Viktoria 1889 Berlin | 9 | 4 | 1 | 4 | 20:18 | 2 | 13 |
| 13 |
|
Niendorfer TSV | 10 | 2 | 4 | 4 | 15:24 | -9 | 10 |
| 14 |
|
SV Meppen | 9 | 1 | 3 | 5 | 12:22 | -10 | 6 |
| 15 |
|
Erzgebirge Aue | 9 | 1 | 2 | 6 | 6:16 | -10 | 5 |
| 16 |
|
Hansa Rostock | 9 | 1 | 2 | 6 | 6:19 | -13 | 5 |
| 17 |
|
FC Carl Zeiss Jena | 9 | 0 | 1 | 8 | 7:30 | -23 | 1 |
| Play-off | |
| Relégation |
